Hydroxypropyl Methyl Cellulose (HPMC, CAS 9004-65-3) is a non-ionic cellulose ether derived from refined cotton linters or wood pulp. Renowned for its thermoplastic and pseudoplastic behavior, HPMC acts as a thickener, water-retention agent, and stabilizer in diverse applications. Its unique ability to modify viscosity, retain moisture, and form films makes it indispensable in industries like:
Key Differentiator: Unlike synthetic polymers, HPMC is biodegradable and non-toxic, complying with eco-certifications like FSC™ and PEFC™ for sustainable sourcing.
HPMC’s performance hinges on precise physicochemical properties. Below are industry-standard specifications validated by USP/EP/JP pharmacopeias and ASTM International testing methods:
Parameter | Specification Range | Industry Standard | Data Source |
---|---|---|---|
Viscosity (2% solution) | 5,000–200,000 mPa·s | USP/EP/JP | [410] |
Moisture Content | ≤5% | USP/EP | [410] |
Ash Content (high-purity) | ≤0.2–1.0% | USP/EP | [46] |
Particle Size | ≥98% through 100 mesh | USP/EP | [410] |
pH (2% solution) | 5.0–8.0 | USP/EP | [410] |
Methoxyl Content | 19–30% | ASTM D3876 | [46] |
Hydroxypropoxyl Content | 7–12% | ASTM D3876 | [46] |
Molecular Weight | ~86 kDa | – | [410] |
Heavy Metals | ≤20 mg/kg | USP/EP | [410] |
Water Retention | >95% (premium grades) | In-house testing | [410] |
Shelf Life | 12–24 months (climate-controlled) | Accelerated aging | [410] |
Note: Premium grades (e.g., Shandong Eaza Chem’s “UltraPure” series) often exceed pharmacopeial limits for ash content (<0.2%) and viscosity stability.
Market Insight: Chinese suppliers (e.g., Lianyungang KANDS) dominate 65% of global production, while European manufacturers focus on niche pharmaceutical grades (20% market share).
Social Media Buzz:
Caution: Beware of suppliers claiming fake ISO certifications; verify via SGS audits or third-party lab reports.
For high-quality HPMC solutions tailored to pharmaceutical and food applications, consider Qingdao ACTA Biotechnology. Their HPMC products stand out for:
Applications:
Why Choose Qingdao ACTA Biotechnology?
The HPMC market in 2025 will favor high-purity, cost-efficient solutions with transparent specifications. Key players like Asahi Kasei and Shandong Eaza Chem are investing in green chemistry to reduce etherification energy costs. Buyers should prioritize suppliers offering:
For deeper insights, explore industry reports from Smithers, Market Research Future, or contact leading manufacturers directly.
[410] HPMC Technical Data Sheet, Shandong Eaza Chem
[46] HPMC Market Analysis, Mordor Intelligence
[412] Global HPMC Production Report, 360 Research Reports
[45] RDP-HPMC Synergy Study, Construction Materials Journal
[414] Gypsum Plaster Innovation, Tai’an Building Materials Institute
[610] Food-Grade HPMC Pricing Index, ICIS