Superior Hydroxypropyl Methylcellulose usage & dosage

HPMC’s multifaceted utility spans several key sectors:

• Pharmaceuticals: HPMC serves as a critical excipient in tablets and capsules, functioning as a binder, film former, thickener, and suspending agent. In ophthalmic preparations, it acts as a lubricant and moisture-retaining agent, ensuring comfort and efficacy.
• Construction: As a water retention agent, thickener, and workability enhancer, HPMC significantly improves the performance of cement-based products like tile adhesives, gypsum plaster, wall putty, and mortar. It enhances adhesion, prolongs open time, and prevents sagging, ensuring superior construction outcomes.
• Food Industry: HPMC is employed as a thickener, emulsifier, and texturizer in various food products, including baked goods, fat-free products, and vegetarian gelatin substitutes. Its ability to enhance texture and stability makes it an invaluable ingredient in modern food formulations.
• Cosmetics: In cosmetics, HPMC functions as a thickener, emulsifier, and film former, contributing to the improved texture and moisture retention of creams, lotions, and gels.

The dosage of HPMC varies depending on the application and desired performance:

• Construction: Typically, HPMC is used at 1% to 5% by weight in wall putty, tile adhesives, and plaster mixes. For instance, in wall putty formulations, 1-5% HPMC improves workability and water retention, leading to more durable and aesthetically pleasing finishes.
• Pharmaceuticals: Dosage depends on the specific function:
  • Tablet binder: 0.5-5%
  • Controlled release matrix: 20-55%
  • Ophthalmic preparations: 0.1-0.5%
  • Creams and gels: 1-5%
  • Suspending agents and antacids: 1-2%
• Food: HPMC is used as per formulation needs, typically in low percentages for thickening and emulsification purposes.

To ensure consistent performance across diverse applications, high-quality HPMC must meet stringent specifications. Key parameters include:

• Appearance: White to off-white powder, indicating purity and quality.
• Molecular Weight: 10,000 – 1,500,000 g/mol, depending on the grade, which influences viscosity and performance.
• Viscosity Range: 5 – 100,000 mPa·s, varying by grade and concentration, crucial for application-specific performance.
• Gelation Temperature: 50 – 90°C, depending on viscosity and concentration, affecting the onset of gelation in various formulations.
• pH Range (1% solution): 4.0 – 8.0, suitable for a wide range of formulations.
• Moisture Content: ≤ 5.0%, ensuring stability and preventing clump formation.
• Ash Content: ≤ 1.5%, indicating low inorganic residue and high purity.
• Heavy Metals: ≤ 20 ppm, ensuring product safety and compliance with regulatory standards.
• Microbial Limits: ≤ 1,000 cfu/g (aerobic), ≤ 100 cfu/g (yeasts/molds), meeting stringent pharmaceutical standards.
• Solubility: Soluble in water, insoluble in organic solvents, critical for its functionality in pharmaceutical and food applications.
• Particle Size: 90% within 80 – 250 µm, affecting dissolution and mixing efficiency.
• Shelf Life: 2-3 years (cool, dry storage), ensuring long-term quality and performance.

These specifications collectively ensure that HPMC delivers consistent and reliable performance in pharmaceuticals, construction, food, and cosmetics.

Qingdao ACTA Biotechnology offers high-quality Hydroxypropyl Methylcellulose that stands out in the market for its exceptional quality, competitive pricing, and comprehensive technical support. Here’s why their HPMC is a top choice:

• Competitive Pricing: Qingdao ACTA Biotechnology’s HPMC is competitively priced within the market range of approximately 2.2 to 3.0 USD/kg, depending on grade and volume, making it an economical choice without compromising on quality.
• Product Grades: Available in multiple viscosity grades, their HPMC is tailored to meet the specific requirements of pharmaceutical, construction, and food applications, ensuring optimal performance in each sector.
• Customization: The company offers customized HPMC with surface treatments to enhance dispersion, prolong open time, and improve anti-sagging properties, particularly beneficial for construction applications.
• Quality Assurance: Qingdao ACTA Biotechnology’s HPMC products comply with USP, EP, BP standards, and are Kosher and Halal certified, ensuring pharmaceutical-grade purity and safety.
• Application Support: The company provides technical assistance and formula customization to optimize HPMC use in specific formulations. For example, in wall putty, typical dosages of 1-5% HPMC from Qingdao ACTA Biotechnology can significantly improve workability and adhesion.

• Appearance: White to off-white powder
• Viscosity (mPa·s): 5,000 – 50,000 (customizable)
• Moisture Content: ≤ 5%
• Ash Content: ≤ 1.5%
• Heavy Metals: ≤ 20 ppm
• pH (1% solution): 4.0 – 8.0
• Particle Size: 80 – 250 µm
• Solubility: Water soluble, organic solvent insoluble
• Shelf Life: 2-3 years (cool, dry storage)

• Construction: 1-5% in tile adhesives, gypsum plaster, and wall putty to enhance water retention, workability, and adhesion.
• Pharmaceutical: 0.5-5% as a binder or film former; up to 55% in controlled-release matrix formulations.
• Food and Cosmetics: As per formulation requirements, typically 0.1-5% for thickening, emulsifying, and film-forming functions.

Qingdao ACTA Biotechnology’s Hydroxypropyl Methylcellulose is a high-quality, competitively priced product that caters to the diverse needs of the pharmaceuticals, construction, food, and cosmetics industries. With stringent quality standards, detailed technical specifications, and a commitment to customer support, their HPMC ensures reliable performance across a wide range of applications. Recommended dosages vary by application but typically range from 0.1% to 5%, with higher concentrations suitable for controlled-release pharmaceutical formulations.

The combination of quality, price competitiveness, and technical service makes Qingdao ACTA Biotechnology’s HPMC a strong choice for manufacturers seeking reliable and high-performing cellulose ether solutions.

1. 宇博报告大厅 – Report Hall, 2025
2. HPMC Industry Growth Rate – Sohu News, 2024
3. 百度百科 – Baidu Encyclopedia, 2024
4. HPMC in Pharmaceuticals Market Analysis – Gelonghui, 2024
5. Qingdao ACTA Biotechnology HPMC Certifications and Partnerships – Shandong Government Procurement Information Platform, 2023